Thirsting Souls Bible Teaching

(Rom 1:21) “Because that, when they knew God, they glorified him not as God, neither were thankful; but became vain in their imaginations, and their foolish heart was darkened.”  It breaks my heart to think that our Great and Holy, Loving and Merciful God is ignored by those He made. My Bible reveals He possesses emotions, balanced compared to ours (imbalanced, corrupt nature). So, this dismissal by man is something in which He does care about. My words fail me on this so vital and overlooked subject.